The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli
نویسندگان
چکیده
منابع مشابه
The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.
BACKGROUND & AIMS The transient receptor potential (TRP) channel family includes transducers of mechanical and chemical stimuli for visceral sensory neurons. TRP ankyrin 1 (TRPA1) is implicated in inflammatory pain; it interacts with G-protein-coupled receptors, but little is known about its role in the gastrointestinal (GI) tract. Sensory information from the GI tract is conducted via 5 affere...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2009
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2009.07.048